| NOUN | act | phase I clinical trial, phase I | a clinical trial on a few persons to determine the safety of a new drug or invasive medical device |
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| Meaning | A clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained. | |
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| Synonym | phase I | |
| Broader | clinical trial, clinical test | A rigorously controlled test of a new drug or a new invasive medical device on human subjects |
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